DTIC AD1002972: RBC Storage Effect on Coagulation pdf

DTIC AD1002972: RBC Storage Effect on Coagulation_bookcover

DTIC AD1002972: RBC Storage Effect on Coagulation

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The study aim is to investigate specific mechanisms of potential adverse effects related to RBC storage age in critically ill patients. Enrollment has been completed since the last report. As of February 4, 2015, we have enrolled 100 of our goal of 100 subjects for testing of immune and coagulation parameters, and 153 of a goal of 200 patients for microchimerism testing. Samples have been collected, processed, and shipped from Canada to the repository at Blood Systems Research Institute (BSRI) in San Francisco, California. The repository consists of plasma, PBMCs and whole blood samples. Cytokine and coagulation testing has been completed for all 100 subjects outlined in the statement of work. Analysis of coagulation, micro particle, microchimerism and immune function testing on study samples is underway, and will be correlated with clinical outcome data shortly when that becomes available

  • Creator/s: Defense Technical Information Center
  • Date: 3/1/2015
  • Year: 2015
  • Book Topics/Themes: DTIC Archive, Spinella, Philip, BLOOD SYSTEMS, INC SCOTTSDALE United States, CLINICAL TRIALS, blood analysis, blood coagulation, cytokines

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