DTIC AD1007167: Building a Better Model: A pdf

DTIC AD1007167: Building a Better Model: A

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Purpose: Development and validation of a personalized breast cancer risk assessment model that includes automated measurement of breast density. Scope: Assemble a cohort of women with known breast cancer risk factors and digital mammogram files for women diagnosed with breast cancer using existing data sources and match them to controls (Harvey/Knaus). Validate and refine automated breast density software (Yaffe/Harvey). Build and validate the initial comprehensive model (Knaus/Yaffe/Harvey).Major Findings: During this second year, we have recruited over 3200 women (622 cases). Breast density measurement has been evaluated for accuracy using a second test set showing very good correlation with 2D methods, for precision using repeated measures with excellent correlation, and variation between vendors. A survey instrument was developed, vetted using focus groups, and administered (nearing completion) to evaluate screening knowledge, practices, and willingness to change practice

• Creator/s: Defense Technical Information Center
• Date: 12/1/2015
• Year: 2015
• Book Topics/Themes: DTIC Archive, Harvey, Jennifer A, The Rector and Visitors of the University of Virginia Charlottesville United States, breast cancer, density, mammography, risk analysis

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