DTIC AD1010641: Early Treatment in Shock. Addendum pdf

DTIC AD1010641: Early Treatment in Shock. Addendum

More Book Details

Description of the Book:

This study has rested on two basic hypotheses. The first is that agents given during and (for a short period of time) after resuscitation can favorably influence the response to hemorrhagic shock and injury. The second is that studies of gene response studies, specifically microarray and RT-PCR studies, could be used to assess the response of patients being treated for injuries to such therapeutic agents. To date, both hypotheses have been shown to be true in the animal model. Three therapeutic agents have been identified, of which glutamine appears to be the most suitable for initial use in patients. Initial clinical studies have been carried out to validate these hypotheses in patients, by using glutamine in patients immediately following resuscitation

• Creator/s: Defense Technical Information Center
• Date: 8/1/2012
• Year: 2012
• Book Topics/Themes: DTIC Archive, Van Way, Charles III, University of Missouri Kansas City United States, hemorrhagic shock, wounds and injuries, resuscitation, genes, Glutamine, proteins, blood cells, hypoxia, Adenosine phosphates, inflammation, gene expression, transcription (genetics), Fatty acids, apoptosis

An excerpt captured from the PDF book