DTIC ADA1029826: Blood Cholinesterase as a Function pdf

DTIC ADA1029826: Blood Cholinesterase as a Function

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The purpose of this research was to document, by the pH method, changes in blood cholinesterase after carbamate poisoning. Five doses of physostigmine and a placebo were injected into rhesus monkeys, and blood samples were taken periodically for 48 hours. Cholinesterase inhibition and behavioral symptoms were most severe during the first 4 hours post injection, and recovery was essentially complete by 8 hours. The results will be used to determine dose and temporal parameters in future studies with physostigmine. (Author

• Creator/s: Defense Technical Information Center
• Date: 7/1/1981
• Year: 1981
• Book Topics/Themes: DTIC Archive, Campbell, Michael E, SYSTEMS RESEARCH LABS INC DAYTON OHIO, *CHOLINESTERASE, *CARBAMATES, *PHYSOSTIGMINE, POISONING, INHIBITION, ERYTHROCYTES, PH FACTOR, BLOOD, RHESUS MONKEYS, BLOOD ANALYSIS

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