DTIC ADA217897: Effects of Dexamethasone and High pdf

DTIC ADA217897: Effects of Dexamethasone and High

More Book Details

Description of the Book:

This study examined the effects of dexamethasone (a potent corticosteroid) to high terrestrial altitude on cognitive performance, affect, and personality traits. Cognitive performance was evaluated by 5 cognitive tasks, affect was evaluated by the Clyde Mood Scale and the Multiple Affect Adjective Check List, and personality traits were examined using the Minnesota Multiphasic Personality Inventory. Sixteen healthy young men received either dexamethasone (4 mg every 6 h) or placebo for 48 h prior to and after ascent to 4300 m. Subjects treated with dexamethasone correctly performed more computer interaction and addition problems than did placebo-treated subjects. They also were less sleepy, dizzy, depressed, and anxious than placebo-treated subjects on the first day at altitude. No adverse effects on cognitive performance, affect, or personality traits were noted after dexamethasone was discontinued on the third day at altitude. Results indicated that dexamethasone at the present dose positively influences cognitive performance and mood states at altitude, but it does not affect personality traits.

Keywords: Cognition/Human performance; Acute mountain sickness

• Creator/s: Defense Technical Information Center
• Date: 12/1/1989
• Year: 1989
• Book Topics/Themes: DTIC Archive, Jobe, Jared B, ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA, *CORTICOSTEROID AGENTS, *ALTITUDE SICKNESS, *COGNITION, HIGH ALTITUDE, ADVERSE CONDITIONS, DAY, PERSONALITY TESTS, MAN COMPUTER INTERFACE, ALTITUDE, PLACEBOS, DOSE RATE, PERSONALITY, POTENCY, ADDITION, MOUNTAINS, STRESS(PHYSIOLOGY), PERFORMANCE(HUMAN), INTERACTIONS

An excerpt captured from the PDF book