DTIC ADA486612: Short Term Exercise and Prostate pdf

DTIC ADA486612: Short Term Exercise and Prostate

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This study seeks to examine the impact of exercise on serum factors related to prostate cancer in African-American men. Aims and Objectives: 1. To recruit 40 African-American men between the ages of 40 and 70 who are at increased risk for developing prostate cancer and randomize them into an exercise intervention or control group. 2. To examine the effect of 12 days of aerobic exercise over 4 weeks on PSA levels in African-American men who have PSA levels under 4.0 ng/ml. 3. To examine the effect of 12 days of aerobic exercise on free and total testosterone, insulin, IGF1, and SHBG levels in African-American men. A total of 40 African-American men between the ages of 40 70 yrs, from the Howard University Cancer Center prostate screening program that have a PSA under 4.0 ng/ml, a BMI 25 and 35 kg/m2, 375 pounds, and have been sedentary for at least 6 months (not exercising for more than 20 minutes 2 days a week).

The men will be randomized into 2 groups 12 days of aerobic exercise (20 participants), or a control group (20 participants). The 12 days of exercise will consist of 30 minutes of walking on a treadmill at 50 60% of maximal heart rate reserve (HRR). Free testosterone, lipids, glucose, insulin, SHBG, psychosocial measures, body weight, BMI and body fat, anthropometric measurements, height, and weight will be measured before and after the study

• Creator/s: Defense Technical Information Center
• Date: 4/1/2008
• Year: 2008
• Book Topics/Themes: DTIC Archive, Taylor, Teletia R, HOWARD UNIV WASHINGTON DC, *PREVENTIVE MEDICINE, *AFRICAN AMERICANS, *TESTOSTERONE, *EXERCISE(PHYSIOLOGY), *SOCIAL PSYCHOLOGY, *PROSTATE CANCER, BODY WEIGHT, GLUCOSE, INSULIN, ANTHROPOMETRY, ADIPOSE TISSUE, RISK, BLOOD SERUM, MALES, SHORT RANGE(TIME), WALKING, AEROBIC PROCESSES

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