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Book Title: DTIC ADA536827: Reconstructing the Prostate Cancer Transcriptional
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Book Category: GENETICS
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Language: english
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Post Date: 2025-04-15 15:55:30
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PDF Size: 1.79 MB
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Book Pages: 36
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DTIC ADA536827: Reconstructing the Prostate Cancer Transcriptional
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Description of the Book:
This award has enabled the development of computational methods to analyze and integrate diverse prostate cancer genomic datasets. We have successfully applied one developed method to a prostate cancer dataset, resulting in the identification of genes that may play a causal role in prostate tumor metastasis. Our analysis of prostate tumor DNA copy number data has also uncovered a potentially novel tumor suppressor gene associated with clinically-indolent prostate cancer. This finding may represent a much-needed biomarker capable of distinguishing indolent versus aggressive disease, and may lead to novel strategies for patient management
- Creator/s: Defense Technical Information Center
- Date: 7/1/2010
- Year: 2010
- Book Topics/Themes: DTIC Archive, , LELAND STANFORD JUNIOR UNIV CA, *TRANSCRIPTION(GENETICS), *PROSTATE CANCER, NUMERICAL METHODS AND PROCEDURES, GENETICS, GENE EXPRESSION, METASTASIS, DEOXYRIBONUCLEIC ACIDS, NEOPLASMS, PROSTATE GLAND
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