DTIC ADA536827: Reconstructing the Prostate Cancer Transcriptional pdf

DTIC ADA536827: Reconstructing the Prostate Cancer Transcriptional

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Description of the Book:

This award has enabled the development of computational methods to analyze and integrate diverse prostate cancer genomic datasets. We have successfully applied one developed method to a prostate cancer dataset, resulting in the identification of genes that may play a causal role in prostate tumor metastasis. Our analysis of prostate tumor DNA copy number data has also uncovered a potentially novel tumor suppressor gene associated with clinically-indolent prostate cancer. This finding may represent a much-needed biomarker capable of distinguishing indolent versus aggressive disease, and may lead to novel strategies for patient management

• Creator/s: Defense Technical Information Center
• Date: 7/1/2010
• Year: 2010
• Book Topics/Themes: DTIC Archive, , LELAND STANFORD JUNIOR UNIV CA, *TRANSCRIPTION(GENETICS), *PROSTATE CANCER, NUMERICAL METHODS AND PROCEDURES, GENETICS, GENE EXPRESSION, METASTASIS, DEOXYRIBONUCLEIC ACIDS, NEOPLASMS, PROSTATE GLAND

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