DTIC ADA580975: SCI with Brain Injury: Bedside pdf

DTIC ADA580975: SCI with Brain Injury: Bedside

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Description of the Book:

Spinal cord injury (SCI) is frequently accompanied by traumatic brain injury (TBI), but evidence-based approaches for treatment of this dual-diagnosis are lacking. This project proposed using current clinical-practice evidence to guide development of an animal model to provide a new tool for studying the biological mechanisms involved, and to open new directions for therapeutics for combined injury. During this second year, we have focused on building a clinical TBI+SCI patient database from the Santa Clara Valley Medical Center and from the VAPAHCS, that details the acute and chronic stages of recovery after dual-injury. This required development of common data elements and methods for querying different types of patient records. We now have an overview of recovery and the medications given to the SCI+TBI patients, and have tracked the duration of all medications prescribed during admission for acute rehabilitation. More medications are used in the dualdual-diagnosisients than for each injury alone.

We have also built a database of SCI+TBI patients from records at SFGH providing information on acute ICU treatment of SCI+TBI patients. These clinical data are now being used to develop hypotheses to test in the newly established model of SCI+TBI during the last year of the grant

• Creator/s: Defense Technical Information Center
• Date: 10/1/2012
• Year: 2012
• Book Topics/Themes: DTIC Archive, , CALIFORNIA UNIV SAN FRANCISCO, *TRAUMATIC BRAIN INJURIES, CLINICAL MEDICINE, DATA BASES, MEDICAL SERVICES, REHABILITATION, SPINAL CORD, THERAPY

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